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Render Timestamp: 2025-03-20T20:04:20.556Z
Commit: 779953b12a5930618aae6aca7c87fb286faeb1d7
XML generation date: 2025-03-07 13:14:18.430
Product last modified at: 2025-03-18T12:15:12.875Z
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PDP - Template Name: Antibody Sampler Kit
PDP - Template ID: *******4a3ef3a

FAK Antibody Sampler Kit #9330

    Product Information

    Product Description

    The FAK Antibody Sampler Kit provides an economical means of evaluating total FAK protein levels as well as FAK phosphorylated at specific sites. The kit contains enough primary and secondary antibody to perform two western blots with each antibody.

    Background

    Focal adhesion kinase (FAK) is a widely expressed cytoplasmic protein tyrosine kinase involved in integrin-mediated signal transduction. It plays an important role in the control of several biological processes, including cell spreading, migration, and survival (1). Activation of FAK by integrin clustering leads to autophosphorylation at Tyr397, which is a binding site for the Src family kinases PI3K and PLCγ (2-5). Recruitment of Src family kinases results in the phosphorylation of Tyr407, Tyr576, and Tyr577 in the catalytic domain, and Tyr871 and Tyr925 in the carboxy-terminal region of FAK (6,7).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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