PTMScan® Direct PI3K/Akt Service 允许对 PI3K/Akt 通路内或者与之相关的一组确定的蛋白质位点进行靶向筛选和定量分析，而且该组蛋白质位点对药物发现、生物标记物发现或诊断学发展至关重要。下表列出了可使用 PTMScan® Direct PI3K/Akt Service 进行监测的蛋白质位点列表。
总而言之，PTMScan® Direct PI3K/Akt 服务提供了一种可定性识别和定量分析 105 种蛋白质的 296 个磷酸化位点的稳健方法。
| PI3K/Akt 蛋白质位点 | |||
|---|---|---|---|
| PI3K/Akt 蛋白质位点 | |||
| 4E-BP1 (Ser35) | 4E-BP1 (Ser44) | 4E-BP1 (Thr36) | 4E-BP1 (Thr37) |
| 4E-BP1 (Thr41) | 4E-BP1 (Thr45) | 4E-BP1 (Thr46) | 4E-BP1 (Thr50) |
| 4E-BP1 (Tyr34) | 4E-BP1 (Tyr54) | 4E-BP2 (Ser44) | 4E-BP2 (Thr36) |
| 4E-BP2 (Thr37) | 4E-BP2 (Thr41) | 4E-BP2 (Thr45) | 4E-BP2 (Thr46) |
| 4E-BP2 (Thr50) | 4E-BP2 (Tyr34) | 4E-BP2 (Tyr54) | 4E-BP3 (Thr23) |
| 4E-BP3 (Thr27) | 4E-BP3 (Thr31) | 4E-BP3 (Thr32) | ACTB (Thr201) |
| ACTG1 (Thr201) | Akt1 (Ser473) | Akt1 (Thr305) | Akt1 (Thr308) |
| Akt1 (Thr312) | Akt1 (Tyr315) | Akt2 (Ser474) | Akt2 (Ser476) |
| Akt2 (Ser478) | Akt2 (Thr309) | Akt2 (Thr313) | Akt2 (Tyr316) |
| Akt2 (Tyr475) | Akt3 (Ser472) | Akt3 (Ser474) | Akt3 (Ser476) |
| Akt3 (Thr298) | Akt3 (Thr305) | Akt3 (Tyr473) | ATR (Ser435) |
| ATR (Ser436) | BAD (Ser71) | BAD (Ser74) | BAD (Ser75) |
| BAD (Ser91) | BAD (Ser97) | BAD (Ser99) | BAD (Thr80) |
| BAD (Tyr76) | CTNND1 iso3 (Ser168) | CTNND1 iso3 (Thr147) | CTNND1 iso3 (Thr149) |
| CTNND1 iso3 (Thr152) | CTNND1 iso4 (Ser168) | CTNND1 iso4 (Thr147) | CTNND1 iso4 (Thr149) |
| CTNND1 iso4 (Thr152) | CTNND1 (Ser168) | CTNND1 (Thr147) | CTNND1 (Thr149) |
| CTNND1 (Thr152) | DNMT1 iso2 (Ser748) | DNMT1 (Ser732) | Dok1 (Tyr341) |
| Dok2 (Tyr299) | eIF4H (Ser230) | eIF4H (Thr217) | eIF4H (Thr220) |
| EphA2 (Thr593) | EphA2 (Thr771) | EphA2 (Thr773) | EphA2 (Thr774) |
| EphA2 (Tyr588) | EphA2 (Tyr772) | FAK iso2 (Ser211) | FAK iso2 (Ser422) |
| FAK iso2 (Thr227) | FAK iso2 (Tyr216) | FAK iso2 (Tyr424) | FAK iso2 (Tyr425) |
| FAK (Ser392) | FAK (Ser574) | FAK (Thr408) | FAK (Tyr397) |
| FAK (Tyr576) | FAK (Tyr577) | FOXK1 (Thr273) | FOXO1A (Ser256) |
| FOXO3A (Ser43) | FOXO3A (Ser48) | FOXO3A (Ser55) | FOXO3A (Thr51) |
| Fyn iso2 (Tyr417) | Fyn (Tyr420) | GAPDH (Thr153) | GOLGA3 (Ser1430) |
| GOLGA3 (Ser983) | GOLGA4 (Ser40) | GOLGA4 (Ser41) | GOLGA4 (Thr39) |
| GOLGA4 (Thr43) | GSK3A (Ser20) | GSK3A (Ser21) | GSK3A (Ser39) |
| GSK3A (Ser41) | GSK3A (Thr19) | GSK3A (Thr46) | HGK iso5 (Ser908) |
| HGK iso5 (Thr187) | HGK iso5 (Thr910) | HGK iso7 (Ser463) | HGK iso7 (Ser934) |
| HGK iso7 (Thr127) | HGK iso7 (Thr936) | HGK (Ser523) | HGK (Ser913) |
| HGK (Thr187) | HGK (Thr915) | HRas (Tyr32) | HRas (Tyr64) |
| IRS1 (Ser303) | IRS1 (Ser307) | IRS1 (Ser312) | IRS1 (Ser315) |
| IRS1 (Ser323) | IRS1 (Ser603) | IRS1 (Ser604) | IRS1 (Ser616) |
| IRS1 (Thr305) | IRS1 (Thr309) | IRS1 (Thr311) | IRS1 (Thr608) |
| IRS1 (Tyr1179) | IRS1 (Tyr612) | IRS2 (Ser594) | IRS2 (Tyr598) |
| KHSRP (Ser132) | KRas iso2 (Tyr32) | KRas iso2 (Tyr64) | KRas (Tyr32) |
| KRas (Tyr64) | lamin A/C iso2 (Ser404) | lamin A/C iso2 (Ser406) | lamin A/C (Ser404) |
| lamin A/C (Ser406) | Lck (Tyr394) | LOC647000 (Ser41) | MEK1 (Ser218) |
| MEK1 (Ser222) | MEK1 (Thr226) | MEK2 (Ser222) | MEK2 (Ser226) |
| MEK2 (Thr230) | MINK iso4 (Thr187) | MINK (Thr187) | MST3 iso2 (Thr170) |
| MST3 iso2 (Thr172) | MST3 iso2 (Thr178) | MST3 iso2 (Thr182) | MST3 (Thr182) |
| MST3 (Thr184) | MST3 (Thr190) | MST3 (Thr194) | MST4 (Thr320) |
| MST4 (Thr327) | mTOR (Ser2442) | mTOR (Ser2448) | mTOR (Ser2450) |
| mTOR (Ser2454) | mTOR (Ser2478) | mTOR (Ser2481) | mTOR (Thr2444) |
| mTOR (Thr2446) | mTOR (Thr2471) | mTOR (Thr2473) | mTOR (Thr2474) |
| mTOR (Tyr2449) | MYPT1 (Ser802) | MYPT1 (Ser910) | MYPT1 (Thr453) |
| MYPT1 (Tyr446) | MYPT1 (Tyr766) | MYPT1 (Tyr901) | MYPT1 (Tyr911) |
| NDRG1 (Ser344) | NDRG1 (Ser352) | NDRG1 (Ser354) | NDRG1 (Ser357) |
| NDRG1 (Ser362) | NDRG1 (Ser364) | NDRG1 (Ser367) | NDRG1 (Ser378) |
| NDRG1 (Ser384) | NDRG1 (Ser389) | NDRG1 (Ser393) | NDRG1 (Thr346) |
| NDRG1 (Thr356) | NDRG1 (Thr360) | NDRG1 (Thr366) | NDRG1 (Thr375) |
| NF-GMB iso2 (Ser134) | NF-GMB iso2 (Tyr131) | NF-GMB (Ser134) | NF-GMB (Tyr131) |
| NF-κB p105 (Ser907) | NRas (Tyr32) | NRas (Tyr64) | Nur77 (Ser351) |
| Nur77 (Ser360) | PAK2 (Ser19) | PAK2 (Ser20) | PAK2 (Ser32) |
| PAK2 (Ser36) | PAK2 (Ser42) | PAK2 (Thr21) | PAK2 (Thr25) |
| PAR-4 (Ser231) | PAR-4 (Ser233) | PAR-4 (Thr229) | PAR-4 (Tyr177) |
| PDK1 iso2 (Ser114) | PDK1 (Ser241) | PDPK2 (Ser214) | PIK3CA (Ser507) |
| PIK3CA (Ser509) | PIK3R1 (Tyr467) | PIK3R2 (Tyr464) | PIK3R3 (Tyr199) |
| PIK3R5 (Ser507) | PIK4CB iso2 (Ser256) | PIK4CB (Ser256) | PKA RI-α (Ser375) |
| PKCα (Thr494) | PKCα (Thr497) | PKCα (Tyr504) | PKCβ iso2 (Thr498) |
| PKCβ iso2 (Thr500) | PKCβ (Thr498) | PKCβ (Thr500) | PKCI (Thr412) |
| PKD2 (Ser375) | PRAS40 (Ser203) | PRAS40 (Thr266) | PTEN (Ser385) |
| RANBP3 iso3 (Ser57) | RANBP3 iso3 (Ser58) | RANBP3 iso3 (Thr56) | RANBP3 iso3 (Thr60) |
| RANBP3 (Ser125) | RANBP3 (Ser126) | RANBP3 (Thr124) | RANBP3 (Thr128) |
| Raptor (Ser719) | Raptor (Ser722) | Rictor (Ser1320) | RSK2 (Ser386) |
| S6 (Ser235) | S6 (Ser236) | S6 (Ser240) | S6 (Ser242) |
| S6 (Ser244) | S6 (Ser246) | S6 (Ser247) | S6 (Thr241) |
| SGK3 (Ser315) | SGK3 (Thr318) | Shb (Ser323) | Shb (Tyr336) |
| SHIP-2 (Tyr886) | Src (Tyr419) | TUBA1A (Ser287) | TUBA1B (Ser287) |
| TUBA3C (Ser287) | TUBA3D (Ser287) | TUBA3E (Ser287) | TUBA4A (Ser287) |
| TUBB2A (Ser339) | TUBB2B (Ser339) | TUBB2C (Ser339) | TUBB3 (Ser339) |
| TUBB4 (Ser339) | TUBB6 (Ser339) | TUBB (Ser339) | XIAP (Ser123) |
| YB-1 (Ser102) | YB-1 (Thr108) | YB-1 (Tyr99) | Yes (Tyr426) |
| YSK1 (Thr166) | YSK1 (Thr168) | YSK1 (Thr174) | YSK1 (Thr178) |