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Render Timestamp: 2024-12-02T06:04:44.814Z
Commit: cd2fae6ca3f811b1ddb1df24ac291ed56d5d501b
XML generation date: 2024-09-20 06:22:46.585
Product last modified at: 2024-10-09T13:00:09.359Z
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PDP - Template Name: Chemical Modulators
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  1. Products /
  2. Proteomic Analysis Products /
  3. Iodoacetamide, PTMScan® Qualified

Iodoacetamide, PTMScan® Qualified #88931

    Product Information

    Product Usage Information

    1. Weigh out 95mg of iodoacetamide and protect from light.

    2. Add reverse osmosis deionized (RODI) water or equivalent to a final volume of 5 ml immediately before use.

    Note: The iodoacetamide solution should be prepared fresh prior to each experiment.

    Storage

    Store lyophilized powder at 4°C, desiccated and protected from light.

    Product Description

    Iodoacetamide is recommended for use in our PTMScan® protocols when making tissue or cell lysates just prior to the digestion steps.
    Purity Greater than or equal to 99%
    Molecular Formula C2H4INO

    Background

    Iodoacetamide is a useful alkylating reagent that modifies cysteine residues so that they can no longer create disulfide linkages. This prevents proteins from refolding and helps to keep them in their primary linear structure to better enable protease digestion and peptide sequencing. This is an irreversible reaction and can also be used for inactivation of enzymes or improved resolution by electrophoresis, where disulfide bonds could potentially reform.

      限制使用

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      For Research Use Only. Not For Use In Diagnostic Procedures.
      Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
      PTMScan is a registered trademark of Cell Signaling Technology, Inc.
      All other trademarks are the property of their respective owners. Visit our Trademark Information page.