Render Target: SSR
Render Timestamp: 2024-11-27T22:45:31.191Z
Commit: d79925545b26f8827f92d145dadc6f0527debdb1
XML generation date: 2024-05-10 22:31:05.816
Product last modified at: 2024-05-30T07:16:01.815Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77

Tyrosinase (T311) Mouse mAb (IHC Specific) #9319

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Inquiry Info. # 9319

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    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 70-80
    Source/Isotype Mouse IgG2a
    Application Key:
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Immunohistochemistry (Paraffin) 1:200

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Specificity / Sensitivity

    Tyrosinase (T311) Mouse mAb detects endogenous levels of total tyrosinase protein.

    Species Reactivity:

    Human

    Source / Purification

    Tyrosinase (T311) Mouse mAb is produced by immunizing animals with a purified recombinant tyrosinase.

    Background

    Tyrosinase, found in the membrane of melanosomes (1), is a key enzyme in the biosynthesis of melanin pigments (1,2). It is a melanocyte differentiation antigen and is expressed in normal melanocytes and malignant melanomas (1,3). Tyrosinase is implicated to be an antigen target for melanoma vaccines (1).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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