Render Target: SSR
Render Timestamp: 2024-10-24T19:49:02.220Z
Commit: 56767fe525c928647c8401233a175d0d607d385d
XML generation date: 2024-08-01 15:28:29.981
Product last modified at: 2024-09-30T16:45:08.795Z
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PDP - Template Name: Polyclonal Antibody
PDP - Template ID: *******59c6464

Phospho-Parkin (Ser108) Antibody #36728

Filter:
  • WB
  • IP

    Supporting Data

    REACTIVITY H
    SENSITIVITY Transfected Only
    MW (kDa) 50
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:50

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    Phospho-Parkin (Ser108) Antibody recognizes transfected levels of Parkin protein only when phosphorylated at Ser108, Ser108/Ser109, and Ser108/Ser110.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser108 of human Parkin protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Background

    Parkin is a protein of 465 amino acids with an amino-terminal ubiquitin domain and a carboxy-terminal RING-box (1). In the case of autosomal recessive juvenile Parkinsonism (AR-JP), deletions have been found in the gene on chromosome 6 encoding the protein Parkin (2).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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