Phospho-p90RSK (Thr359) Matched Antibody Pair #47800
Filter:
- ELISA
Data using Phospho-p90RSK (Thr359) Matched Antibody Pair #47800 are shown. The two antibodies function as a capture-target-detection sandwich (#55773 and #80908, respectively) to detect endogenous protein expression in positive and negative controls.
Supporting Data
| REACTIVITY | H R Mk |
Application Key:
- ELISA-ELISA
Species Cross-Reactivity Key:
- H-Human
- R-Rat
- Mk-Monkey
- Product Includes
- Related Products
| Product Includes | Quantity | Isotype |
|---|---|---|
| Phospho-p90RSK (Thr359) (D1E9) Rabbit mAb (BSA and Azide Free) #55773 | 100 µg | Rabbit IgG |
| RSK1/RSK2/RSK3 (32D7) Rabbit mAb (BSA and Azide Free) #80908 | 100 µg | Rabbit IgG |
Product Information
Product Usage Information
Matched Antibody Pairs consist of capture and detection antibodies that bind to non-overlapping epitopes. For specific identification of the capture and detection antibodies in this pair, please refer to the data figure caption. Optimal dilutions/concentrations should be determined by the end user.
Formulation
Supplied in 1X PBS (10 mM Na2HPO4, 3 mM KCl, 2 mM KH2PO4, and 140 mM NaCl (pH 7.8)). BSA and Azide Free.
Storage
Store at -20ºC. This product will freeze at -20ºC so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Product Description
The Phospho-p90RSK (Thr359) Matched Antibody Pair is ideal for use with immunoassay technologies and high-throughput ELISA platforms requiring antibody pairs with specialized or custom antibody labeling. Labels include fluorophores, lanthanides, biotin, and beads. Platforms requiring conjugated Matched Antibody Pairs include MSD, Quanterix Simoa, Alpha Technology (AlphaScreen, AlphaLISA, LANCE, HTRF), and Luminex.
Learn how Matched Antibody Pairs move your projects forward, faster at cst-science.com/matched-antibody-pairs.
Learn how Matched Antibody Pairs move your projects forward, faster at cst-science.com/matched-antibody-pairs.
Background
The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3).
Pathways
Explore pathways related to this product.
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For Research Use Only. Not For Use In Diagnostic Procedures.
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