Myogenin (LO26) Mouse mAb #59208
Filter:
- IHC
- IF
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | |
| Source/Isotype | Mouse IgG1 |
Application Key:
- IHC-Immunohistochemistry
- IF-Immunofluorescence
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| IHC Leica Bond | 1:50 - 1:200 |
| Immunohistochemistry (Paraffin) | 1:50 |
| Immunofluorescence (Immunocytochemistry) | 1:50 |
Storage
Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 6 months when stored at 4°C. Do not aliquot the antibody.
Protocol
Specificity / Sensitivity
Myogenin (LO26) Mouse mAb recognizes endogenous levels of myogenin protein.
Species Reactivity:
Human
Source / Purification
Monoclonal antibody is produced by immunizing animals with a prokaryotic recombinant fusion protein corresponding to myogenin protein.
Background
Myogenin (MYOG), also called myogenic factor 4 (Myf-4), is a transcriptional regulatory protein that belongs to the myogenic basic helix-loop-helix protein family, which also includes MyoD, Myf-5, and MRF4 (1). It is involved in skeletal muscle development and differentiation and is a marker for myogenesis (1,2). Detection of aberrant myogenin expression is also useful in pathology as an indicator of rhabdomyosarcoma (RMS) (2,3).
限制使用
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For Research Use Only. Not For Use In Diagnostic Procedures.
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