Render Target: SSR
Render Timestamp: 2025-03-06T19:12:40.226Z
Commit: 9fc0f116116d9da247dc8ddd4e5fe811153412e1
XML generation date: 2024-08-01 15:23:58.894
Product last modified at: 2025-02-10T22:30:12.340Z
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PDP - Template Name: Polyclonal Antibody
PDP - Template ID: *******59c6464

HSPA4/Apg-2 Antibody #3303

Filter:
  • WB

    Supporting Data

    REACTIVITY H M R Mk
    SENSITIVITY Endogenous
    MW (kDa) 110
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 
    • Mk-Monkey 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    HSPA4/Apg-2 Antibody detects endogenous levels of total HSPA4 protein.

    Species Reactivity:

    Human, Mouse, Rat, Monkey

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human HSPA4. Antibodies are purified by protein A and peptide affinity chromatography.

    Background

    The heat shock protein HSPA4 (Apg-2, HSP70RY) is a member of the heat-shock protein 110 (Hsp 110) subfamily of Hsp70 heat-shock proteins (1). Apg-2 has chaperone ability similiar to Hsp110, and it plays a role under non-stress conditions (2). Apg-2 interacts with TJP1/ZO-1 and functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress (3,4).
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