Render Target: SSR
Render Timestamp: 2024-11-14T22:46:39.625Z
Commit: 3c1f305a63297e594ac8d7bb5424007d592d68be
XML generation date: 2024-10-29 22:01:07.191
Product last modified at: 2024-11-07T09:00:12.779Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

Glut5 (F4A5K) Rabbit mAb #71407

Filter:
  • WB

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 42-80
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    Glut5 (F4A5K) Rabbit mAb recognizes endogenous levels of total Glut5 protein. This antibody does not cross-react with Glut1, Glut2, Glut3, or Glut4 protein.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Glut5 protein.

    Background

    Glucose transporter 5 (Glut5, also known as SLC2A5) functions as a fructose transporter. Glut5 transports fructose into epithelial cells of small intestine (1,2). Besides the small intestine, Glut5 is also expressed in other tissues, such as skeletal muscle and the prostate gland (3). In addition, studies show that Glut5 expression is significantly upregulated in prostate cancer, and fructose promotes prostate cancer growth (2). Furthermore, fructose metabolism mediated by Glut5 in tumor endothelial cells from hepatocellular carcinoma (HCC) enhances tumor angiogenesis by boosting respiration in mitochondria (4).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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