Render Target: SSR
Render Timestamp: 2024-12-19T21:12:53.250Z
Commit: f2d32940205a64f990b886d724ccee2c9935daff
XML generation date: 2024-09-30 01:59:07.779
Product last modified at: 2024-09-30T08:01:23.912Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

ENPP6 (E7P2Q) Rabbit mAb #95214

Filter:
  • WB

    Supporting Data

    REACTIVITY H M R
    SENSITIVITY Endogenous
    MW (kDa) 50
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    ENPP6 (E7P2Q) Rabbit mAb recognizes endogenous levels of total ENPP6 protein.

    Species Reactivity:

    Human, Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro65 of mouse ENPP6 protein.

    Background

    Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) is a choline-specific glycerophosphodiesterase that belongs to the ENPP family. The seven ENPP family members play different biological roles in nucleotide and phospholipid signaling, bone mineralization, fibrotic diseases, and tumor-associated immune cell infiltration. ENPP6 is GPI-anchored to the plasma membrane and contains a PDE domain (1). This enzyme hydrolyzes polyunsaturated lysophosphatidylcholine (LPC), glycerophosphorylcholine (GPC), or sphingosylphosphorylcholine (SPC) in kidney and brain (2). It can be used as a marker of newly-forming oligodendrocytes in mouse brain (3). 
    For Research Use Only. Not For Use In Diagnostic Procedures.
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