Androgen Receptor (Carboxy-terminal Antigen) Matched Antibody Pair #32477
Filter:
- ELISA
Data using Androgen Receptor (Carboxy-terminal Antigen) Matched Antibody Pair #32477 are shown. The two antibodies function as a capture-target-detection sandwich (#54524 and #76452, respectively) to detect endogenous expression of protein in positive and negative controls.
Supporting Data
| REACTIVITY | H |
Application Key:
- ELISA-ELISA
Species Cross-Reactivity Key:
- H-Human
- Product Includes
- Related Products
| Product Includes | Quantity | Isotype |
|---|---|---|
| Androgen Receptor (E9L1Z) Rabbit mAb (Carboxy-terminal Antigen) (BSA and Azide Free) #54524 | 100 µg | Rabbit IgG |
| Androgen Receptor (A3H8W) Rabbit mAb (BSA and Azide Free) #76452 | 100 µg | Rabbit IgG |
Product Information
Product Usage Information
Matched Antibody Pairs consist of capture and detection antibodies that bind to non-overlapping epitopes. For specific identification of the capture and detection antibodies in this pair, please refer to the data figure caption. Optimal dilutions/concentrations should be determined by the end user.
Formulation
Supplied in 1X PBS (10 mM Na2HPO4, 3 mM KCl, 2 mM KH2PO4, and 140 mM NaCl (pH 7.8)). BSA and Azide Free.
Storage
Store at -20ºC. This product will freeze at -20ºC so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Product Description
Background
Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3).
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For Research Use Only. Not For Use In Diagnostic Procedures.
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