Render Target: SSR
Render Timestamp: 2024-10-24T19:28:14.241Z
Commit: 56767fe525c928647c8401233a175d0d607d385d
XML generation date: 2024-05-10 22:31:21.618
Product last modified at: 2024-10-11T12:00:34.830Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77

α-Synuclein (Syn204) Mouse mAb #2647

Filter:
  • WB

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 18
    Source/Isotype Mouse IgG2a
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    α-Synuclein (Syn204) Mouse mAb detects endogenous levels of total synuclein protein. α-Synuclein (Syn204) Mouse mAb detects recombinant α but not β-synuclein (Giasson, B.I. et al., 2000).

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a recombinant human α-synuclein protein.

    Background

    α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinson's disease (1).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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