渲染靶标:SSR
Render Timestamp: 2025-04-02T07:50:04.416Z
Commit: 779953b12a5930618aae6aca7c87fb286faeb1d7
XML generation date: 2025-03-07 13:17:00.948
Product last modified at: 2025-03-10T18:30:10.980Z
1% for the Planet 标识
PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

α-Synuclein (E4U2F) XP® Rabbit mAb (BSA and Azide Free) #45083

Filter:
  • WB
  • IHC
  • IF
Western Blotting Image 1: α-Synuclein (E4U2F) XP® Rabbit mAb (BSA and Azide Free)
Western blot analysis of extracts from mouse and rat brain using α-Synuclein (E4U2F) XP® Rabbit mAb. Data were generated using the standard formulation of this product.

To Purchase # 45083

Supporting Data

REACTIVITY H M R
SENSITIVITY Endogenous
MW (kDa) 18
Source/Isotype Rabbit IgG
Application Key:
  • WB-Western Blotting 
  • IHC-Immunohistochemistry 
  • IF-Immunofluorescence 
Species Cross-Reactivity Key:
  • H-Human 
  • M-Mouse 
  • R-Rat 
  • Related Products

Product Information

Product Usage Information

This product is the carrier-free version of product #51510. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.

This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN, or CUT&Tag assays. If you require a carrier-free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.

BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.

Formulation

Supplied in 1X PBS (10 mM Na2HPO4, 3 mM KCl, 2 mM KH2PO4, and 140 mM NaCl (pH 7.8)). BSA and Azide Free.

For standard formulation of this product see product #51510.

Storage

Store at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.

Specificity / Sensitivity

α-Synuclein (E4U2F) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total α-Synuclein protein. This antibody does not cross-react with β-Synuclein. Weak nuclear staining of uncertain specificity was observed in limited ovarian tumors by immunohistochemistry.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human α-Synuclein protein

Background

α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinson's disease (1).

Pathways

Explore pathways related to this product.


For Research Use Only. Not For Use In Diagnostic Procedures.
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