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Render Timestamp: 2024-12-04T09:09:42.000Z
Commit: cd2fae6ca3f811b1ddb1df24ac291ed56d5d501b
XML generation date: 2024-10-25 16:21:15.165
Product last modified at: 2024-10-26T07:00:55.899Z
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PDP - Template Name: Chemical Modulators
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Docetaxel #9886

    Product Information

    Product Usage Information

    Docetaxel is supplied as 1 mg powder. Store at or below -20ºC. Before use, dissolve powder in 1 ml DMSO to make a 1 mg/ml stock solution. The suggested working concentration is 100 ng/ml in tissue culture medium. Treat cells for 4-24 hours. Store solution at -20ºC.

    Storage

    Store lyophilized or in solution at -20ºC, desiccated. In lyophilized form, the chemical is stable for 24 months. Once in solution, use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Product Description

    Molecular Weight 807.88 g/mol
    Purity >99%
    Molecular Formula C43H53NO14
    CAS 114977-28-5
    Solubility Soluble in DMSO at 200mg/ml and EtOH at 100mg/ml.

    Background

    Docetaxel belongs to the taxane family of antitumor and antileukemic agents (1). A microtubule-stabilizing agent, docetaxel acts as an inhibitor of cellular functions that require microtubule dynamics including cell division, and is now in use as a treatment for breast, prostate and lung cancer (2).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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